domains / families / science / validation-strategy-designer

validation-strategy-designer

separate

Designs internal, external, temporal, and functional validation strategies at the protocol stage for medical research studies.

When to use

• biomarker studies
• prognostic and response-prediction studies
• cohort and real-world evidence studies
• bulk omics studies
• single-cell-guided studies
• MR / QTL follow-up studies
• translational studies
• mechanism-to-validation planning

When not to use

• pretending that every study must include every validation tier
• inventing animal or cell experiments without support
• claiming external validation is available when no suitable independent cohort exists
• treating internal resampling as equivalent to independent validation
• converting a discovery study into a confirmatory study by wording alone

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