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two-sample-mr-research-planner

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Generates complete two-sample Mendelian randomization (MR) research designs from a user-provided research direction. Use when users want to design, plan, or build a study using two-sample MR to test causal relationships. Triggers:"design a two-sample MR study", "build a publishable MR paper", "test whether this biomarker causally affects this disease", "generate Lite/Standard/Advanced MR plans", "screen multiple exposures with MR", "bidirectional MR design", "causal inference using GWAS summary statistics", or "I want to study X and Y using MR". Always outputs four workload configurations (Lite / Standard / Advanced / Publication+) with a recommended primary plan, step-by-step workflow, figure plan, validation strategy, minimal executable version, and publication upgrade path.

When to use

• design a two-sample MR study
• build a publishable MR paper
• test whether this biomarker causally affects this disease
• generate Lite/Standard/Advanced MR plans
• screen multiple exposures with MR
• bidirectional MR design
• causal inference using GWAS summary statistics
• study X and Y using MR

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