domains / families / science / jaspar-database

jaspar-database

separate

Query JASPAR for transcription factor binding site (TFBS) profiles (PWMs/PFMs). Search by TF name, species, or class; scan DNA sequences for TF binding sites; compare matrices; essential for regulatory genomics, motif analysis, and GWAS regulatory variant interpretation.

When to use

• **TF binding site prediction**: Scan a DNA sequence for potential binding sites of a TF
• **Regulatory variant interpretation**: Does a GWAS/eQTL variant disrupt a TF binding motif?
• **Promoter/enhancer analysis**: What TFs are predicted to bind to a regulatory element?
• **Gene regulatory network construction**: Link TFs to their target genes via motif scanning
• **TF family analysis**: Compare binding profiles across a TF family (e.g., all homeobox factors)
• **ChIP-seq analysis**: Find known TF motifs enriched in ChIP-seq peaks
• **ENCODE/ATAC-seq interpretation**: Match open chromatin regions to TF binding profiles

Skill page

Source