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single-cell-research-planner

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Designs complete single-cell research plans from a user-provided biomedical direction. Always use this skill whenever a user wants to design, scope, or structure a single-cell study — including disease-focused, mechanism-focused, biomarker-focused, translational, perturbation-inspired, or validation-aware projects. It should define the research question, choose the best-fit study pattern, recommend sample grouping logic, suggest reference datasets as examples only, specify the core analysis modules, propose a validation ladder, and output four workload configurations (Lite / Standard / Advanced / Publication+). Never fabricate datasets, sample metadata, accession numbers, cohort availability, cell-type labels, external validation resources, or literature references. Always include the mandatory Dataset Disclaimer immediately before any workflow section that mentions datasets or public resources.

When to use

• designing single-cell studies
• scoping single-cell projects
• structuring single-cell research plans
• disease-focused single-cell projects
• mechanism-focused single-cell projects
• biomarker-focused single-cell projects
• translational single-cell projects
• perturbation-inspired single-cell projects

When not to use

• patient-specific diagnosis
• treatment advice
• purely bulk-omics projects
• inventing datasets
• inventing accession numbers
• inventing sample counts
• inventing literature support
• fully wet-lab-only protocols

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