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bio-single-cell-perturb-seq

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Analyze Perturb-seq and CROP-seq CRISPR screening data integrated with scRNA-seq. Use when identifying gene function through pooled genetic perturbations in single cells.

When to use

• Perturb-seq CRISPR screen analysis
• CROP-seq data integration
• Linking guide RNA assignments to transcriptional phenotypes
• Identifying gene function via pooled genetic perturbations
• Perturbation classification using Mixscape
• Differential expression per perturbation
• Perturbation embedding and clustering
• Guide assignment from CRISPR feature barcode

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