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bio-clinical-databases-polygenic-risk

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Calculate polygenic risk scores using PRSice-2, LDpred2, or PRS-CS from GWAS summary statistics. Use when predicting disease risk from genome-wide genetic variants.

When to use

• Calculate polygenic risk scores
• Predict disease risk from genome-wide genetic variants
• Compute genome-wide risk scores
• Bayesian PRS with LDpred2
• PRS using continuous shrinkage priors
• Score normalization
• Risk stratification

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