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reactome

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Query the Reactome REST API for pathway content and enrichment analyses; use when you need curated pathway data, reaction details, or overrepresentation results for a gene list.

When to use

• You have a list of genes/proteins and want to run pathway overrepresentation (enrichment) analysis against Reactome.
• You need to retrieve curated pathway content (hierarchy, reactions, participants) by Reactome stable IDs (e.g., `R-HSA-69278`).
• You want to map expression values onto pathways to support pathway-level interpretation.
• You need to project pathways across species/organisms using Reactome’s species projection capabilities.
• You are building a systems biology workflow that requires programmatic access to Reactome via its REST API.

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