domains / families / science / mendelian-randomisation

mendelian-randomisation

separate

A specialized agent for running two-sample Mendelian Randomisation with multiple estimators and a complete sensitivity analysis panel from GWAS summary statistics.

When to use

• **One skill, one task.** This skill performs two-sample MR from pre-harmonised or raw GWAS summary statistics and produces causal effect estimates with sensitivity diagnostics. It does not perform GWAS, LD score regression, colocalization,…

When not to use

• GWAS association study
• Single variant lookup
• Polygenic risk scores
• Colocalization analysis
• LD score regression
• Multi-trait analysis

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