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deepspot-m

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Generates transcriptome-wide virtual spatial transcriptomics from H&E histology with DeepSpot-M. Used for predicted log1p-CPM expression from 224x224 tiles at about 20x, querying the released protein-coding gene panel by symbol, and whole-slide prediction after resolution-aware tiling with histolab.

When to use

• Virtual spatial transcriptomics generation
• Predicted log1p-CPM expression
• 224x224 H&E tile processing
• Whole-slide prediction
• Resolution-aware tiling
• Querying protein-coding gene panel

When not to use

• Clinical or diagnostic use
• Commercially funded or collaborative use
• Querying genes outside the released ~19k panel

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