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lncrna-regulatory-network-construction-analysis

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Use this bioinformatics data analysis skill to construct a database-driven lncRNA-mRNA regulatory network from target lncRNA and/or gene lists by projecting shared miRNA evidence from local ceRNA reference tables. It does not infer networks from expression matrices.

When to use

• Build an lncRNA-mRNA network from target genes and the bundled ceRNA reference tables
• Start from a candidate lncRNA list and retrieve linked mRNAs through shared miRNAs
• Generate an auditable lncRNA-mRNA network table plus a tripartite evidence table
• Reuse a saved database-derived network object to regenerate a PDF plot
• Expression-matrix-based network inference
• Correlation analysis between lncRNAs and mRNAs
• Causal inference or regulatory-strength estimation from expression data
• Online database querying or remote API lookups

When not to use

• Expression-matrix-based network inference
• Correlation analysis between lncRNAs and mRNAs
• Causal inference or regulatory-strength estimation from expression data
• Online database querying or remote API lookups

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