domains / families / science / bio-tcr-bcr-analysis-immcantation-analysis

bio-tcr-bcr-analysis-immcantation-analysis

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Analyze BCR repertoires for somatic hypermutation, clonal lineages, and B cell phylogenetics using the Immcantation framework. Use when studying B cell affinity maturation, germinal center dynamics, or antibody evolution.

When to use

• BCR repertoire analysis
• somatic hypermutation analysis
• clonal lineage reconstruction
• B cell phylogenetics
• affinity maturation tracking
• germline inference
• selection pressure testing

When not to use

• TCR-focused diversity metrics
• general tree concepts

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