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gtex-database

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Query GTEx (Genotype-Tissue Expression) portal for tissue-specific gene expression, eQTLs (expression quantitative trait loci), and sQTLs. Essential for linking GWAS variants to gene regulation, understanding tissue-specific expression, and interpreting non-coding variant effects.

When to use

• **GWAS locus interpretation**: Identifying which gene a non-coding GWAS variant regulates via eQTLs
• **Tissue-specific expression**: Comparing gene expression levels across 54 human tissues
• **eQTL colocalization**: Testing if a GWAS signal and an eQTL signal share the same causal variant
• **Multi-tissue eQTL analysis**: Finding variants that regulate expression in multiple tissues
• **Splicing QTLs (sQTLs)**: Identifying variants that affect splicing ratios
• **Tissue specificity analysis**: Determining which tissues express a gene of interest
• **Gene expression exploration**: Retrieving normalized expression levels (TPM) per tissue

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