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tf-target-gene-regulatory-network

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Use when analyzing transcription factor (TF) regulatory networks using Dorothea database. Input gene list, identify regulating transcription factors, generate TF-Target network visualization. For: transcription factor enrichment analysis, gene regulatory network research.

When to use

• Use this skill when you have a human or mouse gene list and want to identify upstream TFs from the Dorothea database.
• Use it when you need a ready-to-export TF-target network table plus a publication-ready PDF network plot.
• Use it for reproducible CLI execution with saved session information and optional local Dorothea `.rds` databases.

When not to use

• Do not use this skill for differential expression, pathway enrichment, cell type annotation, or survival analysis.
• Do not use it to infer causal direction beyond curated Dorothea TF-target relationships.
• Do not use it when your input genes are aliases or mixed-species symbols that have not been normalized first.

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