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dbsnp-queries

separate

Resolves rsIDs, navigates RsMergeArch/SNPHistory merge chains, and converts between rsID, SPDI, HGVS, and VCF representations using the dbSNP Build 156 JSON architecture. Use when normalizing variant identifiers, joining variant databases by cluster ID, or tracking deprecated rsIDs through historical merges.

When to use

• normalizing variant identifiers
• joining variant databases by cluster ID
• tracking deprecated rsIDs through historical merges
• resolving rsIDs through merge chains
• computing canonical SPDI
• converting between rsID, HGVS-g, HGVS-c, and VCF allele representations
• resolving single rsID to coordinates + alleles
• resolving historical/deprecated rsID

When not to use

• using rsIDs as variant identifiers for multi-allelic sites
• relying on Entrez for full build-156 schema fields

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