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bio-ctdna-mutation-detection

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Detects somatic mutations in circulating tumor DNA using variant callers optimized for low allele fractions with UMI-based error suppression. Reliably detects mutations at VAF above 0.5 percent using consensus-based approaches. Use when identifying tumor mutations from plasma DNA or tracking specific variants.

When to use

• Identifying tumor mutations from plasma DNA
• Tracking specific variants
• Detecting somatic variants at low allele fractions
• Minimal residual disease monitoring
• Quantifying variant allele fraction of known mutations

When not to use

• sWGS data analysis

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