domains / families / science / bio-cfdna-preprocessing

bio-cfdna-preprocessing

separate

Preprocesses cell-free DNA sequencing data including adapter trimming, alignment optimized for short fragments, and UMI-aware duplicate removal using fgbio. Applies cfDNA-specific quality thresholds and fragment length filtering. Use when processing plasma cfDNA sequencing data before downstream analysis.

When to use

• processing plasma cfDNA sequencing data
• UMI extraction
• consensus calling
• error suppression
• sensitive variant detection
• fragment size analysis

Skill page

Source