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bulk-to-single-deconvolution

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Turn bulk RNA-seq cohorts into synthetic single-cell datasets using omicverse's Bulk2Single workflow for cell fraction estimation, beta-VAE generation, and quality control comparisons against reference scRNA-seq.

When to use

• reconstruct single-cell profiles from bulk RNA-seq
• cell fraction estimation
• beta-VAE generation
• quality control comparisons against reference scRNA-seq
• harmonise bulk replicates
• generate synthetic cells
• benchmark output cells against reference atlas

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