domains / families / science / brenda-database

brenda-database

combined

Access BRENDA enzyme database via SOAP API. Retrieve kinetic parameters (Km, kcat), reaction equations, organism data, and substrate-specific enzyme information for biochemical research and metabolic pathway analysis. Programmatic access to the BRENDA enzyme database via the SOAP API; use when you need kinetic constants (Km, kcat, Vmax), reaction equations, enzyme properties (pH/temperature optima, stability), or enzyme discovery by EC/substrate/product.

When to use

• Searching for enzyme kinetic parameters (Km, kcat, Vmax)
• Retrieving reaction equations and stoichiometry
• Finding enzymes for specific substrates or reactions
• Comparing enzyme properties across different organisms
• Investigating optimal pH, temperature, and conditions
• Accessing enzyme inhibition and activation data
• Supporting metabolic pathway reconstruction and retrosynthesis
• Performing enzyme engineering and optimization studies

When not to use

• Do not use this skill when the required source data, identifiers, files, or credentials are missing.
• Do not use this skill when the user asks for fabricated results, unsupported claims, or out-of-scope conclusions.
• Do not use this skill when a simpler direct answer is more appropriate than the documented workflow.

Skill page

Conflict

Both copies describe the same BRENDA SOAP workflow, but each contains material steps the other lacks. The aipoch copy defines the concrete runtime contract (zeep/requests, BRENDA_EMAIL/BRENDA_PASSWORD, scripts/brenda_queries.py, BrendaClient, response delimiter parsing, validation/failure handling). The FreedomIntelligence copy adds a richer query surface (organism/substrate filters, reaction search, enzyme discovery by substrate/product/pattern, cross-organism comparison, environmental parameters, cofactors, substrate specificity) and parsing helpers. Crowning one would hide either the operational setup or the expanded query capabilities.