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bio-methylation-bismark-alignment

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Bisulfite sequencing read alignment using Bismark with bowtie2/hisat2. Handles genome preparation and produces BAM files with methylation information. Use when aligning WGBS, RRBS, or other bisulfite-converted sequencing reads to a reference genome.

When to use

• aligning WGBS reads
• aligning RRBS reads
• aligning bisulfite-converted sequencing reads
• genome preparation for bisulfite sequencing
• PBAT library alignment
• non-directional library alignment

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