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bio-atac-seq-footprinting

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Detect transcription factor binding sites through footprinting analysis in ATAC-seq data using TOBIAS. Use when identifying TF occupancy patterns within accessible regions, as TF binding protects DNA from Tn5 cutting.

When to use

• Identify TF binding footprints in ATAC-seq data
• Detect protected DNA regions within accessible chromatin
• Compare TF binding between two conditions
• Identify regulators with differential activity
• Extract and visualize aggregate ATAC-seq signal around predicted TF binding sites
• Scan for motifs in peaks

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