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disease-mechanism-evidence-map

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Systematically maps mechanism evidence for a disease from molecules to pathways, cell types, tissues, biological consequences, and clinical phenotypes. Always use this skill when a user needs a layered mechanism evidence chain rather than a flat summary or immediate gap analysis. Formal literature citations must be real and verifiable.

When to use

• Rapid understanding of disease mechanism architecture
• Mechanism hypothesis building before study design
• Disease introduction / discussion framework construction
• Mechanism-oriented evidence synthesis before gap analysis
• Mechanism-chain inspection for translational thinking
• Whole-disease mechanism landscape
• Stage-specific mechanism mapping
• Organ- or tissue-focused mechanism mapping

When not to use

• Flat literature summary
• Generic pathway list
• Formal gap-finder
• Completed protocol writer
• Formal causal proof
• Protocol design

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