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cosmic-database

combined

Access COSMIC cancer mutation database. Query somatic mutations, Cancer Gene Census, mutational signatures, gene fusions, for cancer research and precision oncology. Requires authentication. Access COSMIC to download mutation datasets, query Cancer Gene Census, and retrieve mutational signatures when your genomic analysis requires curated somatic mutation resources.

When to use

• Downloading cancer mutation data from COSMIC
• Accessing the Cancer Gene Census for curated cancer gene lists
• Retrieving mutational signature profiles
• Querying structural variants, copy number alterations, or gene fusions
• Analyzing drug resistance mutations
• Working with cancer cell line genomics data
• Integrating cancer mutation data into bioinformatics pipelines
• Researching specific genes or mutations in cancer contexts

Skill page

Conflict

Both copies describe the same COSMIC download workflow, but the FreedomIntelligence copy adds material steps and constraints the aipoch copy lacks: command-line usage with --data-type and --assembly flags, an output_filename parameter, a list of available data types (fusions, copy number, resistance), genome assembly guidance (GRCh37 vs GRCh38), versioning notes, and pysam for VCF. The aipoch copy adds a py_compile validation step and a references/ pointer. Because each has steps the other lacks, crowning one would hide a real alternative.